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Sweating is the release of water from sweat glands in the skin. It is a major mechanism of heat control in a human and in larger animals.
Sweat glands are under the control of the sympathetic nervous system. The sympathetic nerves insert into the sweat glands in the skin. When the nerves fire an impulse, sweat is released from the glands.
When Botulinum toxin is injected under the skin in clinical doses and volumes, an area of approximately half a centimetre in all directions is affected and stops sweating. This is because the Botulinum toxin binds with the ends of the sympathetic nerves and so the sweat gland cannot function anymore.
It is possible that the sweat gland will start sweating again in the future when the sympathetic nerves grow a new end plate which then attaches to the sweat glands. This usually happens six to nine months after the injection but can be as fast as three months or can be as long as 12 months.
Only small areas can be treated using this technique and it is usually reserved for the underarms (axillae) only. Some people have tried using it for hands and feet but this can be very painful and is not usually successful for the sweating between the fingers and toes, and along the fingers and toes themselves.
(More information can be found on www.sweating.co.uk) |
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